The Industrys Most Popular Molecular Cloning Tool

The easiest way to plan, visualize and document your everyday molecular cloning procedures

Improve accuracy while moving faster, so you save time and money.

Elegant, information-rich windows for simulating common cloning and PCR methods

Clear visual schematics let you see exactly how your construct will be put together

SnapGene helps you identify and avoid common mis-steps by keeping track of details like DNA methylation and phosphorylation

With unparalleled visibility and control, even novice cloners will quickly accomplish complex tasks.

Gain unparalleled visibility of your DNA or protein sequence

Create and browse richly annotated plasmid maps or scan large DNA sequences with thousands of annotated features

Confirm your cloning results with highly visual alignment of sequencing results to your simulated construct

Automatic documentation of simulated procedures saves time and makes sharing and saving work easier, more efficient, and more effective.

Automatically generate a rich graphical history of every sequence edit and cloning procedure

Enhance collaboration and retain knowledge by sharing constructs complete with the historical details of how it was made

Experiment confidently with comprehensive undo capabilities that retrace your steps

I just want to say that I LOVE SnapGene. It has dramatically altered the research that my lab does, giving us the confidence to take on difficult cloning with minimal effort!

Beyond the Basics of Molecular Cloning

SnapGene is the most popular cloning tool for a reason. Its fast, smart and extremely user-friendly

Intuitive technology identifies design flaws in cloning procedures so they can be corrected

Simulate standard PCR using your own primers, or allow SnapGene to design them automatically

Specialised cloning tools ensure fast accurate construct design for all major molecular cloning techniques

SnapGene is the most intuitive, easy to use cloning program I have ever been able to get my hands on.

Verify your project design and prevent errors

Automatically View Plasmid Features

Annotate features on your plasmids using SnapGenes curated feature database or your own custom features

Display enzyme sites, features, primers, ORFs, translations and more on plasmid maps or in detail on the sequence view

Customize your maps with flexible annotation and visualization controls

Check Your Sequences with Alignment Tools

Validate your sequenced constructs match your simulated construct using the powerful Align to Reference tool

Align sequences using trusted algorithms for pairwise and multiple alignments, including Clustal Omega, MAFFT, MUSCLE and T-Coffee

Assemble Sanger sequencing reads into complete contigs using CAP3

Visualise exactly what you will see in the lab with SnapGenes empirically based gel simulation algorithm

Flexible configuration of all gel elements, including number of lanes, % agarose, running time and a full set of MW markers

Record and identify your band of interest with detailed fragment information for each lane

Beautiful graphic interface especially for marking features and multiple sequence alignments. THANK YOU!!

UT Health Science Center, San Antonio

Configured for automatic documentation and easy data exchange

Automatically Create a Graphical History

Record experimental procedures and changes to documents visually

Show history colors in history, map and sequence views

Fully resurrectable sequence history embedded in the document

Store, search, share and organize your sequences, files and maps

Work collaboratively with sequences in collections stored on sharable drives, servers or cloud services

Easily read and export sequences, annotations and other metadata from manycommon file formats

The history feature (my favorite) keeps track of each step, and any construct I get from colleagues comes complete with how it was made. I recommend this software to anyone who clones DNA.

Explore a list of SnapGenes robust set of features designed to enhance your everydaymolecular cloning procedures

Anneal two oligos to form a double-stranded product

Predefined enzyme sets - by company or cutter

Rich support for methylation sensitivity and associated error prevention

Automatic annotation of common features

Sophisticated numbering of feature translations

Check reading frames for gene fusions

Align DNA sequences with a reference sequence

Pairwise and multi sequence DNA and Protein alignment

Choice of alignment algorithms - Clustal Omega, MAFFT, MUSCLE, T-Coffee

See multiple views of a DNA sequence

Large sequence support - browse chromosome size sequences

See a graphical history of a product

Use optional history colors to identify the most recent change to a sequence

Import fromcommon file formatsincluding annotations and notes

Search for DNA or protein sequences

Search for enzymes, features or primers

Cross platform compatibility - Windows, macOS, Linux

Discover the mostuser-friendlymolecular biology experience